On the relief of bronchospasm and the induction of alveolar hyperventilation: a comparative study of nebulized bronchodilators by deep breathing and intermittent positive pressure.

The introduction of aerosol therapy1”2 with bronchodilator drugs has added much to the management of obstructive pulmonary insufficiency.’ It is thought to be superior to oral and parenteral administration although comparative controlled data is lacking on this point.3 Since the combination of aerosol bronchodilators administered with intermittent positive pressure breathing (IPPB) , superior results have been obtained to conventional inhalation methods.”’7 Other comparative studies,8’9 however, have contested the superiority of aerosol-IPPB therapy.